by Rafael Bañes / May 16, 2024
Researchers from the University of Chicago have created new devices called “living bioelectronics” that may play a big role in addressing skin conditions. The laboratory, which was led by Professor Bozhi Tian, created the device to confront the problems rooted in traditional bioelectronics, aiming to avoid skin irritation and rigidity.
Tian’s laboratory researches the relationship that living cells and tissues have with synthetic materials when they interact, such as the usual bioelectronic, which contains an electronic component and a soft layer to battle the irritation. For this study, instead of the standard bioelectronic, Tian’s group decides to approach this differently. Here’s how.
The device, which takes on the form of an applicable patch, comprises three components. The first component, which contains the electronic factor of the device, utilizes a thin and flexible electronic circuit. This circuit is then covered with gel that includes tapioca starch and gelatin. However, a third component brings living bacterial cells into the mix, specifically one called staphylococcus epidermidis. This microbe, which naturally lives on human skin, plays the most crucial role in this new bioelectronic, known for its anti-inflammatory properties that live on the skin. Being inserted into the gel, when the patch is applied to the skin,
The bioelectronic, which includes the new component of living cells, was tested on mice, and there was an overall improvement in the skin conditions and a decrease in skin irritation. They continued the tests for a week using a platform called Active Biointegrated Living Electronics (ABLE), meaning that these devices can be easily rehydrated for multiple uses. Tian’s laboratory hopes to use the ABLE system for another half-year, as the device can be freeze-dried for storage and replenished.
Beyond treating psoriasis, scientists and researchers see a future in which the patch can be used for patients with other conditions, such as diabetes. Tian also sees an approach of various tissues and cell types with the patch in the future, mentioning possible devices that can produce insulin or interact with neurons.
Although there are still many steps on the way, the progress that has been made in bioelectronics is significant, and may change the way we confront sickness in the future.
Citations
Chicago, U. of. (2024, June 2). 15 years in the making – scientists invent “living bioelectronics” That can heal skin. SciTechDaily. https://scitechdaily.com/15-years-in-the-making-scientists-invent-living-bioelectronics-that-can-heal-skin/
McMillan, T. (2024, June 10). Scientists develop breakthrough “Living bioelectronics” to heal skin and revolutionize medical treatment. The Debrief. https://thedebrief.org/scientists-develop-revolutionary-living-bioelectronics-to-heal-skin-and-revolutionize-medical-treatment/
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